• Windows Logo + D
  This handy shortcut minimises all open windows and takes you to the desktop.
• Alt + Tab (or in Vista: Windows Logo + Tab)
  Allows you to switch between open applications easily. This shortcut looks even better in Windows Vista as it gives you a preview of the windows you have open.
  
• Windows Logo + R
  Opens the Windows Run dialogue box
  
• Alt + F4
  Closes the application you currently have open.
• Ctrl + Alt + Delete
  Allows you to view the Windows Task Manager, which lets you terminate processes/applications.
  
• Ctrl + X (Cut), Ctrl + C (Copy), Ctrl + P (Paste)
  Although this is technically three shortcuts they should be used together, the cut, copy and paste shortcuts allow you to cut, copy and paste any text, image or document from one location to another.
• Windows Key + F1
  Quickly opens Windows Help and Support which gives you access to a large archive of support documentation for Windows written by Microsoft.

If we’ve missed your favorite, please let us know!